The firm has proposed no longer providing audit and account and compliance and reporting services at the Inverness office, offering these services from alternative locations in Scotland and Newcastle instead.
The proposed restructure puts 35 audit and compliance workers at risk of losing their jobs.
A spokesperson for the firm said, "EY can confirm that it is proposing to cease the provision of audit and account, compliance and reporting services from the Inverness office, with the intention to continue to deliver this service to our clients from other locations in Scotland and Newcastle.
"As a result, it is with regret that 35 people have been placed at risk of redundancy and a consultation process has begun."
The Big Four firm added that it hopes to relocate some staff, if possible.
"We do, of course, hope to explore other opportunities for individuals within EY, if skills are transferable.
"EY remain committed to the Inverness market and our assurance business in Scotland as a whole."
The spokesperson added that the tax team in Inverness is unaffected by the decision.