The news of Granger’s departure comes two days after it was announced that the Revenue’s head of customer services Ruth Owen is to leave after only a year in the job. She is taking a job in the private sector.
Granger has led the HMRC compliance department for five years.
Granger said, “Leaving HMRC will be really difficult. I can honestly say that this has been one of the best and most rewarding roles that I’ve ever had. I’ve enjoyed my time here so much that I actually stayed here far longer than I originally planned to.
“It’s also time for a little bit of rebalancing for me personally. So while I’ll be sad to go, it’s definitely the right time, both for me and for HMRC.”
HMRC said it will start recruiting a successor in early April.
During Granger’s leadership, HMRC introduced new compliance tools such as the direct recovery of debt and accelerated payments and saw its revenue collected through compliance work rise to £26.6bn last year.
The department also recruited 12,000 people into compliance and opened Basecamp to support the development of the next generation of compliance staff.